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The SLITRK4-CNPY3 axis promotes liver metastasis of gastric cancer by enhancing the endocytosis and recycling of TrkB in tumour cells

2022-12-07

Abstract excerpt

<h4>Purpose: </h4> Gastric cancer (GC) is a malignant tumour with high mortality, and liver metastasis is one of the main causes of poor prognosis. SLIT- and NTRK-like family member 4 ( SLITRK4 ) plays an important role in the nervous system, such as synapse formation. Our study aimed to explore the functional role of SLITRK4 in GC and liver metastasis. Methods The mRNA level of SLITRK4 was evaluated using public...

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Literature Corpus work
d247cd6a-ddd7-5896-8601-224f47667ec2
DOI
10.21203/rs.3.rs-2329872/v1
Open publication

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The SLITRK4-CNPY3 axis promotes liver metastasis of gastric cancer by enhancing the endocytosis and recycling of TrkB in tumour cellsDOI 10.21203/rs.3.rs-2329872/v1
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