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An integrated ‘omics approach highlights the role of epigenetic events to explain and predict response to neoadjuvant chemotherapy and bevacizumab

2022-07-07

Abstract excerpt

Here we present an integrated ‘omics approach for DNA methylation profiling using copy number alteration, gene expression and proteomic data to predict response to therapy and to pinpoint response-related epigenetic events. Fresh frozen tumor biopsies taken before, during and after treatment from patients receiving neoadjuvant chemotherapy with or without the anti-angiogenic drug bevacizumab were subjected to mole...

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Literature Corpus work
d23735a8-0073-5a0d-8d67-d2b6b80dd02b
DOI
10.1101/2022.07.06.498803
Open publication

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An integrated ‘omics approach highlights the role of epigenetic events to explain and predict response to neoadjuvant chemotherapy and bevacizumabDOI 10.1101/2022.07.06.498803
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