Article

Conserved transcriptomic profile between mouse and human colitis allows temporal dynamic visualization of IBD-risk genes and unsupervised patient stratification

2019-01-16

Abstract excerpt

<h4>Abstrasct</h4> Despite the fact that ulcerative colitis (UC) patients show heterogeneous clinical manifestation and diverse response to biological therapies, all UC patients are classified as one group. Therefore, there is a lack of tailored therapies. In order to design these, an unsupervised molecular re-classification of UC patients is evoked. Classical clustering approaches based on tissue transcriptomic...

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Literature Corpus work: d20fc10c-16bd-5f55-b48b-8350ad7936c2
DOI: 10.1101/520379

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