Article

Human ZKSCAN3 and <i>Drosophila</i> M1BP are functionally homologous transcription factors in autophagy regulation

2019-08-27

Abstract excerpt

Autophagy is an essential cellular process that maintains homeostasis by recycling damaged organelles and nutrients during development and cellular stress. ZKSCAN3 is the sole identified master transcriptional repressor of autophagy in humans. How ZKSCAN3 achieves autophagy repression at the mechanistic or organismal level however still remains to be elucidated. Here, we demonstrate that vertebrate ZKSCAN3 and Dro...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d1ec2c80-c3ed-53fd-a766-71be81860a97
DOI: 10.1101/747824

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Human ZKSCAN3 and <i>Drosophila</i> M1BP are functionally homologous transcription factors in autophagy regulationDOI 10.1101/747824Read

ZKSCAN3 Is a Master Transcriptional Repressor of AutophagySemantic proximity Read

Transcriptional regulation of autophagy and its implications in human diseaseSemantic proximity Read

ZKSCAN3 counteracts cellular senescence by stabilizing heterochromatinSemantic proximity Read

CHD1L augments autophagy-mediated migration of hepatocellular carcinoma through targeting ZKSCAN3Semantic proximity Read

Endogenous HMGB1 regulates autophagySemantic proximity Read

A coherent FOXO3-SNAI2 feed-forward loop in autophagySemantic proximity Read

Autophagy Regulatory Network — A systems-level bioinformatics resource for studying the mechanism and regulation of autophagySemantic proximity Read

Au_Sus: A tiered consensus census of human autophagy genesSemantic proximity Read

A gene toolbox for monitoring autophagy transcriptionSemantic proximity Read

AutophagyNet: High-resolution data source for the analysis of autophagy and its regulationSemantic proximity Read

GLIS1–3 transcription factors: critical roles in the regulation of multiple physiological processes and diseasesSemantic proximity Read

Histone demethylases in autophagy and inflammationSemantic proximity Read