Back to search

Article

Network Pharmacology-Based Exploration of Complementary Molecular Mechanisms of Heat-Clearing (Scutellariae Radix, Coptidis Rhizoma) and Blood-Tonifying Herbs (Angelicae Sinensis Radix, Paeoniae Radix Alba) in Cold Hypersensitivity in Hands and Feet

2026-07-29

Abstract excerpt

Cold hypersensitivity in hands and feet (CHHF) affects 20–52% of East Asian populations, is more prevalent in women, and is managed with vasodilators in Western medicine or herbal therapies in traditional East Asian medicine. This study was conducted to compare the pharmacological characteristics of two heat-clearing (HCHs, Scutellariae Radix and Coptidis Rhizoma) and two blood-tonifying herbs (BTHs, Angelicae Sin...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
d16f109a-fe18-5c43-8f28-e6acaabf4e37
DOI
10.20944/preprints202607.2151.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Network Pharmacology-Based Exploration of Complementary Molecular Mechanisms of Heat-Clearing (Scutellariae Radix, Coptidis Rhizoma) and Blood-Tonifying Herbs (Angelicae Sinensis Radix, Paeoniae Radix Alba) in Cold Hypersensitivity in Hands and FeetDOI 10.20944/preprints202607.2151.v1
Integrating Pharmacokinetics and Network Analysis to Investigate the Mechanism of Moutan Cortex in Blood-Heat and Blood Stasis SyndromeSemantic proximity
HR-LCMS and Network Pharmacology-based immunity enhancing and pulmonary protection activity of a polyherbal Ayurveda formulationSemantic proximity
Exploring the active components and potential mechanisms of Qingre Liangxue Decoction in the treatment of psoriasis vulgaris with blood-heat syndrome based on UHPLC-Q-exactive Orbitrap/MS and network pharmacologySemantic proximity
From Transcriptomic Signatures to Active-Site Docking and ADMET Properties Prediction: Bioinformatics-Guided Exploration of Binding Mechanisms of Cardioprotective Phytoconstituents Against Dysregulated Targets in Hypertrophic CardiomyopathySemantic proximity
Network analysis of the pharmacological mechanism of Reduning injection in the treatment of novel coronavirus pneumoniaSemantic proximity
Network pharmacology and bioinformatics analyses identify the intersection genes and mechanism of Huangbai for Recurrent Aphthous StomatitisSemantic proximity
Chuanxiong Rhizoma regulates ferroptosis and the immune microenvironment in ischemic stroke through the JAK-STAT3 pathwaySemantic proximity
Mechanism of Clinacanthus nutans against hepatic fibrosis based on network pharmacology and molecular dockingSemantic proximity
Study on the discovery of lung-descending herbs and bioactive constituents using TRP channel-functionalized screeningSemantic proximity
Network pharmacology and bioinformatics analyses identify the intersection genes and mechanism of Huang Bai for recurrent aphthous stomatitisSemantic proximity
Therapeutic Role and Potential Mechanism of Astragalus Membranaceus (Huangqi) and Radix Paeoniae Rubra (Chishao) in Idiopathic Pulmonary Fibrosis – Network Pharmacology and Experimental ValidationSemantic proximity
Network-Based Gene Expression Biomarkers for Cold and Heat Patterns of Rheumatoid Arthritis in Traditional Chinese MedicineSemantic proximity
Select a neighboring publication to make it the new centre.