Article

Compensating Cortical Thickness for Cortical Folding-Related Variation

2025-05-05

Abstract excerpt

Cortical thickness is a widely used biomarker of brain morphology and health, yet it is dependent on local cortical folding. Because gyral crowns are consistently thicker than sulcal fundi and cortical folds vary widely across individuals, these fluctuations introduce unmodeled nuisance variance that can obscure meaningful biological effects of interest. Previous global methods of folding compensation incompletely...

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Literature Corpus work: d0f48c4b-7ab6-52c3-b78f-d82d6cc39638
DOI: 10.1101/2025.05.03.651968

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