Article

ModVAR: A Multimodal Framework for Comprehensive Driver Variant Prediction in Cancer

2024-09-17

Abstract excerpt

<title>Abstract</title> <p>Cancer's genomic complexity poses significant challenges in identifying the crucial driver variants that fuel oncogenesis. To overcome these obstacles, we present ModVAR, an innovative multimodal model that seamlessly integrates DNA sequences, protein tertiary structures, and cancer omics data to predict driver variants with exceptional precision. Leveraging pre-trained models DNAbert2...

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Literature Corpus work: cfd8821b-4d1f-583e-98c9-33ad811e60d8
DOI: 10.21203/rs.3.rs-4969792/v1

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