Article

Oncolytic adenovirus encoding LHPP exerts potent antitumor effect in lung cancer

2024-02-21

Abstract excerpt

LHPP has been shown to be a new tumor suppressor, and has a tendency to be under-expressed in a variety of cancers. Oncolytic virotheray is a promising therapeutics for lung cancer in recent decade years. Here we successfully constructed a new recombinant oncolytic adenovirus GD55-LHPP and investigated the effect of GD55-LHPP on the growth of lung cancer cells in vitro and in vivo. The results showed that LHPP had...

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Literature Corpus work: cf90265f-6c2f-5a84-8080-697ec17f4cc2
DOI: 10.21203/rs.3.rs-3888343/v1

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