Article

Inhibition of the Receptor for Advanced Glycation End-Products in Acute Respiratory Distress Syndrome: A Randomised Laboratory Trial in Piglets

2018-08-31

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The receptor for advanced glycation end products (RAGE) modulates the pathogenesis of acute respiratory distress syndrome (ARDS). RAGE inhibition was recently associated with attenuated lung injury and restored alveolar fluid clearance (AFC) in a mouse model of ARDS. However, clinical translation will first require assessment of this strategy in larger animals. <h4>Methods</...

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Literature Corpus work: cf422a7f-3bd9-572d-bbea-4ff8bc9dca90
DOI: 10.1101/405423

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