Article

Circulating-blood dose is associated with severe lymphopenia in thoracic radiotherapy, but added simulation complexity provides no detectable incremental information

2026-08-17

Abstract excerpt

<h4>Purpose</h4> To compare scalar circulating-blood dose summaries, assess whether associations with grade 3 or higher lymphopenia and overall survival persisted after planning target volume (PTV) adjustment, and distinguish scalar from exploratory dynamic blood-dose analyses. <h4>Methods and Materials</h4> The assembled dataset included 133 patients from 2 retrospective thoracic radiation cohorts; 121 entered...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cdcdee8e-9459-565f-9b81-bdf616737cec
DOI: 10.64898/2026.08.13.26359883

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Circulating-blood dose is associated with severe lymphopenia in thoracic radiotherapy, but added simulation complexity provides no detectable incremental informationDOI 10.64898/2026.08.13.26359883Read

Radiation-Induced Lymphopenia: In Silico Replications of Preclinical Studies Suggest Importance of Dose to Lymphoid OrgansSemantic proximity Read

First Measurement: Proactive Immune Cell Sparing in Radiation TherapySemantic proximity Read

Serum miRNA-based signature indicates radiation exposure and dose in humans: a multicenter diagnostic biomarker studySemantic proximity Read

Genomic-Adjusted Radiation Dose from Bulk RNA Sequencing for Personalized RadiotherapySemantic proximity Read

Is it necessary to prescribe the same dose to subclinical lesions as gross tumor volume in non-small-cell lung cancer? —a failure pattern analysisSemantic proximity Read

Correlation between pelvic bone marrow dose volume parameters and acute hematologic toxicity in neoadjuvant intensity-modulated radiotherapy for locally advanced rectal cancerSemantic proximity Read

Radiation-induced lymphopenia during chemoradiation therapy for non-small cell lung cancer is linked with age, lung V5, and XRCC1 rs25487 genotypes in lymphocytes.Semantic proximity Read

Introduction to Clinical Radiation BiologySemantic proximity Read

Interim Analysis of Dose-Escalated Preoperative Breast Irradiation: A Phase Ib studySemantic proximity Read

Optimizing Clinical Outcome and Toxicity in Lung Cancer Using a Genomic Marker of RadiosensitivitySemantic proximity Read

Estimated absolute benefit of adjuvant endocrine therapy after partial-breast irradiation in hormone receptor-positive early breast cancer: a calibrated competing-risks scenario analysis of randomized-trial dataSemantic proximity Read

Clinically Validated Model Predicts the Effect of Intratumoral Heterogeneity on Overall Survival for Non-Small Cell Lung Cancer (NSCLC) PatientsSemantic proximity Read