Article

Histone Deacetylase-2 Serves as an Independent Prognostic Indicator in Osteosarcoma

2020-12-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Osteosarcoma is the most common primary malignant tumor of skeleton in adolescence. Histone deacetylase 2 (HDAC2), a member of class I histone deacetylase, is putatively involved in tumorigenesis of human malignancies. This study aimed to evaluate the expression pattern and prognostic value of HDAC2 in osteosarcoma.<bold>Methods</bold> Four datasets were obtained...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cd3e7155-4591-5990-a9e3-ed996eb726a7
DOI: 10.21203/rs.3.rs-127806/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Histone Deacetylase-2 Serves as an Independent Prognostic Indicator in OsteosarcomaDOI 10.21203/rs.3.rs-127806/v1Read

A novel histone acetylation-associated gene signature with prognostic value in Ewing SarcomaSemantic proximity Read

A Prognostic Model for the Overall Survival of Patients with Ewing's SarcomaSemantic proximity Read

Wnt Signaling Pathway Related Gene CTNNBIP1 Act as A potential Prognostic Biomarker and A Comprehensive Prognostic Analysis in OsteosarcomaSemantic proximity Read

HDAC2 promotes cell migration/invasion abilities through HIF-1α stabilization in human oral squamous cell carcinomaSemantic proximity Read

Screening of diagnostic markers for osteosarcomaSemantic proximity Read

Expression Profile Analysis Identifies Key Genes as Prognostic Markers for Metastasis of OsteosarcomaSemantic proximity Read

Integrated multiomic analysis and high‐throughput screening reveal potential gene targets and synergetic drug combinations for osteosarcoma therapySemantic proximity Read

Osteosarcoma transcriptome data exploration reveals STC2 as a novel risk indicator in disease progressionSemantic proximity Read

Genomic nursing science revealed the prolyl 4-hydroxylase subunit alpha 2 as a significant biomarker involved in osteosarcomaSemantic proximity Read

Identification of genes that influence poor prognosis in osteosarcomaSemantic proximity Read

IRF2 Destabilizes Oncogenic KPNA2 to Modulate the Tumorigenesis of Osteosarcoma via Regulating NF-κB/p65Semantic proximity Read

Sox2 is required for tumor development and cancer cell proliferation in osteosarcomaSemantic proximity Read