Article

Generation of Dyskeratosis Congenita-like Hematopoietic Stem Cells through the Stable Inhibition of DKC1

2021-01-05

Abstract excerpt

<title>Abstract</title> <p>Dyskeratosis congenita (DC) is a rare telomere biology disorder, which results in different clinical manifestations, including severe bone marrow failure. To date, the only curative treatment for bone marrow failure in DC patients is allogeneic hematopoietic stem cell transplantation. However due to the toxicity associated to this treatment, improved therapies are recommended for DC pat...

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Literature Corpus work: cd3118eb-b234-5297-b253-eba00f73198b
DOI: 10.21203/rs.3.rs-26927/v3

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