Article

Role of the reactive oxygen species induced DNA damage in human spermatozoa dysfunction

2018-01-26

Abstract excerpt

Abstract: Non-enzymatic oxidative damage of DNA in the male germ cell line is believed to be one of the key mechanisms of premature apoptosis of spermatozoa and in pathogenesis of male subfertility. High motility of sperm cells requires high activity of energetic metabolism and mitochondrial functioning that makes them subject to excessive influence of reactive oxygen species (ROS). Low volume of cytoplasm, where...

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Literature Corpus work: cd244f29-62c3-5862-bc8a-82aa5064c681
DOI: 10.21037/amj.2018.01.06

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