Article

ProLLM: Protein Chain-of-Thoughts Enhanced LLM for Protein-Protein Interaction Prediction

2024-04-21

Abstract excerpt

The prediction of protein-protein interactions (PPIs) is crucial for understanding biological functions and diseases. Previous machine learning approaches to PPI prediction mainly focus on direct physical interactions, ignoring the broader context of nonphysical connections through intermediate proteins, thus limiting their effectiveness. The emergence of Large Language Models (LLMs) provides a new opportunity for...

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Literature Corpus work: ccf0d5ee-de66-5be1-b4b1-6ae95d284178
DOI: 10.1101/2024.04.18.590025

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