Article

Multifractal Fluctuations in Electrogram Dynamics Distinguish Atrial Fibrillation Phenotype, Drug Response, and Imminent Termination: Implications for Mechanism and Treatment

2026-04-15

Abstract excerpt

<h4>Structured Abstract</h4> <h4>Background</h4> Atrial fibrillation (AF) is maintained by complex dynamics, clinically characterised by bursting periods of organization and disorganization in intracardiac electrograms. We have previously postulated that cardiac conduction behaves like a critical system, where phase shift from organised rhythm to AF is a phase transition at the critical point. We thus hypothesiz...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ccb70354-fbff-5f24-9720-d037d243f2cb
DOI: 10.64898/2026.04.12.718068

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Multifractal Fluctuations in Electrogram Dynamics Distinguish Atrial Fibrillation Phenotype, Drug Response, and Imminent Termination: Implications for Mechanism and TreatmentDOI 10.64898/2026.04.12.718068Read

AF-FLOW Global Registry Confirms Validity of Electrographic Flow Mapping as a Phenotyping Tool for Atrial Fibrillation.Semantic proximity Read

Autonomics, More Than Fibrosis, Predict Postoperative Atrial FibrillationSemantic proximity Read

In-silico assessment of the dynamic effects of amiodarone and dronedarone on human atrial patho-electrophysiology.Semantic proximity Read

AI-based derivation of atrial fibrillation phenotypes in the general and critical care populations.Semantic proximity Read

Transcriptome and proteome mapping in the sheep atria reveal molecular featurets of atrial fibrillation progressionSemantic proximity Read

Analysis of the Time-Dependent Behaviors of Atrial Fibrillation with Electrographic Flow MappingSemantic proximity Read

ECG-I phenotyping of persistent AF based on driver burden and distribution to predict response to pulmonary vein isolation (PHENOTYPE-AF).Semantic proximity Read

Clinical phenotypes in acute and chronic infarction explained through human ventricular electromechanical modelling and simulationsSemantic proximity Read

Prediction of Medically Drug-Induced Arrhythmias (Torsades de Pointes, Ventricular Tachycardia, and Ventricular Fibrillation) in Rabbit Model up to One Hour Before Their Onset Using Computational Method Based on Entropy Measure and Machine LearningSemantic proximity Read

Electrophysiological and molecular mechanisms of paroxysmal atrial fibrillation.Semantic proximity Read

How often should we monitor for reliable detection of atrial fibrillation recurrence? Efficiency considerations and implications for study design.Semantic proximity Read

Circadian Patterns of Wearable-Derived Electrocardiographic Age and Left Atrial Remodeling in AF-Naïve IndividualsSemantic proximity Read