Article

Systematic assessment of multi-gene predictors of pan-cancer cell line sensitivity to drugs exploiting gene expression data

2017-03-14

Abstract excerpt

<h4>Background: </h4> Selected gene mutations are routinely used to guide the selection of cancer drugs for a given patient tumour. Large pharmacogenomic data sets, such as those by Genomics of Drug Sensitivity in Cancer (GDSC) consortium, were introduced to discover more of these single-gene markers of drug sensitivity. Very recently, machine learning regression has been used to investigate how well cancer cell l...

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Literature Corpus work: ccaf0a8f-9510-5a3f-ae5a-9f1340339064
DOI: 10.12688/f1000research.10529.2

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