Human stool preservation impacts taxonomic profiles in 16S rRNA gene-based metagenomics studies

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Microbiotas play critical roles in human health, yet in most cases scientists lack standardized and reproducible methods. To date, stool sample preservation remains a source of technological bias in metagenomic sequencing, despite newly developed storage solutions. Studying those biases will help in identifying the appropriate stool preservation approach to prom...

Topics

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• Clostridium difficile and Clostridium perfringens research
• Colorectal Cancer Screening and Detection
• Diet and metabolism studies
• Fecal contamination and water quality
• Gut microbiota and health
• Metabolomics and Mass Spectrometry Studies
• Molecular Biology Techniques and Applications
• Mycobacterium research and diagnosis

Identifiers and source

Literature Corpus work

cc88b8b8-c2df-5a66-8808-5e8a0ba1a397

DOI

10.21203/rs.3.rs-87437/v1