Article

Combining Single-Cell and Bulk RNA Sequencing Data to Create a Reliable Prognostic Model for Predicting Clear-cell Renal Cell Carcinoma Progression

2026-06-01

Abstract excerpt

<title>Abstract</title> <p> <bold>Introduction:</bold> Clear-cell renal cell carcinoma (ccRCC) is the most common pathological type of kidney cancer and is characterized by a low survival rate. Accurate prediction ofthe occurrence and progression of ccRCC is crucial for diagnosis and treatment. This study aimed to integrate multiple publicly available bulk sequencing and single-cell datasets onccRCC to establis...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cc2c7a44-deff-5cf4-aacf-75b6f8e1c65f
DOI: 10.21203/rs.3.rs-6711579/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Combining Single-Cell and Bulk RNA Sequencing Data to Create a Reliable Prognostic Model for Predicting Clear-cell Renal Cell Carcinoma ProgressionDOI 10.21203/rs.3.rs-6711579/v1Read

Identification of a differentiation-related prognostic nomogram based on single-cell RNA sequencing in clear cell renal cell carcinomaSemantic proximity Read

Integrated analysis of single-cell and transcriptome based RNA-seq multilayer network and WGCNA for construction and validation of an immune cell-related prognostic model in clear cell renal cell carcinomaSemantic proximity Read

Identification of prognostic genes in kidney renal clear cell carcinoma by RNA-seq data analysisSemantic proximity Read

Identification of G protein-coupled receptor gene and immune infiltration analysis to construct a prognostic model for renal clear cell carcinoma patientsSemantic proximity Read

Establishment of a Seven-Gene Signature Associated with CD8+ T Cells through the Utilization of Both Single-Cell and Bulk RNA-Sequencing Techniques in Clear Cell Renal Cell CarcinomaSemantic proximity Read

NETosis-based prognostic model reveals immune modulation in clear cell renal cell carcinoma using single-cell and bulk RNA sequencingSemantic proximity Read

Clinical value and in vitro validation of gene and molecular subtype identification in renal clear cell carcinomaSemantic proximity Read

Bioinformatics profiling integrating a three immune-related long non-coding RNA signature as a prognostic model for clear cell renal cell carcinomaSemantic proximity Read

Single-Cell RNA Sequencing in Multiple Pathologic Types of Renal Cell Carcinoma Revealed Novel Potential Tumor-Specific MarkersSemantic proximity Read

Prediction of clear cell renal cell carcinoma prognosis based on an immunogenomic landscape analysisSemantic proximity Read

A novel prognostic model based on immunogenomics for clear cell renal cell carcinoma.Semantic proximity Read

Transcriptomic characterization and innovative molecular classification of clear cell renal cell carcinoma in the Chinese populationSemantic proximity Read