Article

Pharmacokinetics and Dialytic Clearance of Apixaban During In Vitro Continuous Renal Replacement Therapy

2020-10-27

Abstract excerpt

<title>Abstract</title> <p><bold>Objective: </bold>To evaluate the transmembrane clearance (CL<sub>TM</sub>) of apixaban during modeled <italic>in vitro</italic> continuous renal replacement therapy (CRRT), assess protein binding and circuit adsorption, and provide initial dosing recommendations. <bold>Design: </bold><italic>In vitro</italic> pharmacokinetic (PK) study.<bold>Setting: </bold>University research la...

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Literature Corpus work: cb66c0d5-36f6-5794-b1ce-d7ed8bed02eb
DOI: 10.21203/rs.3.rs-58735/v2

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