Article

Multiscale three-dimensional imaging of intact human organs down to the cellular scale using hierarchical phase-contrast tomography

2021-02-03

Abstract excerpt

<h4>ABSTRACT</h4> Human organs are complex, three-dimensional and multiscale systems. Spatially mapping the human body down through its hierarchy, from entire organs to their individual functional units and specialised cells, is a major obstacle to fully understanding health and disease. To meet this challenge, we developed hierarchical phase-contrast tomography (HiP-CT), an X-ray phase propagation technique util...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cb16a7d0-592c-582d-ae14-427e6f363813
DOI: 10.1101/2021.02.03.429481

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Multiscale three-dimensional imaging of intact human organs down to the cellular scale using hierarchical phase-contrast tomographyDOI 10.1101/2021.02.03.429481Read

A multiscale X-ray phase-contrast tomography dataset of whole human left lungSemantic proximity Read

Multidimensional Analysis of the Adult Human Heart in Health and Disease using Hierarchical Phase-Contrast Tomography (HiP-CT)Semantic proximity Read

The Human Organ AtlasSemantic proximity Read

Evolution of Hierarchical Phase-Contrast Tomography on the European Synchrotron beamlines BM05 and BM18: a whole adult human brain imaging case studySemantic proximity Read

Multiscale Segmentation using Hierarchical Phase-contrast Tomography and Deep LearningSemantic proximity Read

Whole human organ clearing and multimodal mappingSemantic proximity Read

A whole-organ multi-scale in silico framework for human kidney haemodynamics informed by hierarchical phase-contrast tomographySemantic proximity Read

The Extremely Brilliant Brain: An Isotropic Microscale Human Brain DatasetSemantic proximity Read

A high-throughput 3D X-ray histology facility for biomedical research and preclinical applicationsSemantic proximity Read

Computational and Imaging Approaches for Precision Characterization of Bone, Cartilage, and Synovial BiomoleculesSemantic proximity Read

Depth-Variant Deconvolution Applied to Widefield Microscopy for Rapid Large-Volume Tissue ImagingSemantic proximity Read

A nanopathology pipeline for clinical research across scales using human tissueSemantic proximity Read