Article

Knockdown of TRAF1 in NSCIC Contributes Gefitinib Sensitivity by Promoting G2/M Cell Cycle Arrest

2021-11-02

Abstract excerpt

<h4>Background: </h4> Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) achieves remarkable success in the treatment of patients with advanced non-small cell lung cancer (NSCLC) bearing activating EGFR mutations. However, EGFR-TKI resistance is still a obstacles in the clinical practice. TRAF1 as a member of TRAF family participates NSCLC progression. In our previous research found that TRAF1...

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Literature Corpus work: ca92b61e-1567-5bb2-bdb4-c6da67722651
DOI: 10.21203/rs.3.rs-1014136/v1

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