Article

Regulation of spatial and temporal gene expression in an animal germline

2018-06-15

Abstract excerpt

<h4>SUMMARY</h4> In animal germlines, regulation of cell proliferation and differentiation is particularly important but poorly understood. Here, using a cryo-cut approach, we mapped RNA expression along the Caenorhabditis elegans germline and, using mutants, dissected gene regulatory mechanisms that control spatio-temporal expression. We detected, at near single-cell resolution, > 10,000 mRNAs, > 300 miRNAs and...

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Literature Corpus work: ca74c131-4c48-5aec-a991-3564bf384122
DOI: 10.1101/348425

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