Article
Comparative evaluation of imputation and batch-effect correction for proteomics/peptidomics differential-expression analysis
2025-08-16
Abstract excerpt
Mass spectrometry (MS)-based proteomics offers powerful opportunities for biomarker discovery; nevertheless, it is associated with technical challenges, some of them being missing values and batch effects. Both can obscure biological signal and bias results. Although imputation and batch-correction methods are well established in transcriptomics, their impact, particularly on large-scale, real-world clinical prote...
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Identifiers and source
- Literature Corpus work
- c9b6d31c-2ceb-5f4f-ba3b-ecf079c54ef1
- DOI
- 10.1101/2025.08.14.25333694