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Blocking TIGIT/CD155 Signal Reverses CD8+T Cell Exhaustion and Enhances the Anti-Tumor Ability of Cervical Cancer

2022-02-28

Abstract excerpt

<h4>Objective: </h4> ： TIGIT/CD155 has attracted widespread attention as a new immune checkpoint and a potential target for cancer immunotherapy. In our study, we evaluated the role of TIGIT/CD155 checkpoints in the progression of cervical cancer.Methods. Detect the expression of CD155 and TIGIT in cervical cancer tissues by flow cytometry, immunohistochemistry and gene expression profiling. In vivo and in vitro e...

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Literature Corpus work
c8f0d627-709b-54d8-8885-4643ca36d505
DOI
10.21203/rs.3.rs-1353432/v1
Open publication

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Blocking TIGIT/CD155 Signal Reverses CD8+T Cell Exhaustion and Enhances the Anti-Tumor Ability of Cervical CancerDOI 10.21203/rs.3.rs-1353432/v1
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