Diagnostic Challenge of Occult ER-Positive Breast Carcinoma within Bone Marrow Indolent B-Cell Lymphoma and Response to CDK4/6 Inhibitor: a case report

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Bone marrow metastasis from hormone receptor–positive breast cancer can be challenging to detect, especially in patients with concurrent hematologic malignancies, where isolated epithelial cells may be hidden by a dominant lymphoid infiltrate. This situation requires careful histopathologic and immunophenotypic evaluation to prevent misdiagnosis. <bold>Case p...

Topics

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• Biomarkers, Tumor
• Breast Neoplasms
• Circulating Tumor DNA
• High-Throughput Nucleotide Sequencing
• Immunohistochemistry
• In Situ Hybridization, Fluorescence
• Mutation
• Pathology, Molecular

Identifiers and source

Literature Corpus work

c89590e8-5004-5682-b2b5-fa6a5e9f9343

DOI

10.21203/rs.3.rs-9236922/v1