Article

In Vivo Mechanical Assessment of Cortical Bone Rigidity Enhances Fracture Discrimination Beyond DXA in Postmenopausal Women

2025-08-29

Abstract excerpt

<h4>ABSTRACT</h4> Dual-energy x-ray absorptiometry (DXA)-derived areal bone mineral density (BMD) remains the clinical standard for assessing osteoporosis risk, yet it fails to identify over 75% of individuals who sustain fragility fractures. Direct in vivo mechanical assessment of cortical bone strength may address this diagnostic gap by capturing structural and material properties that govern whole-bone strengt...

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Literature Corpus work: c871111d-eace-5a18-9b11-12f55097823c
DOI: 10.1101/2025.08.28.25334655

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