Article

Rates and spectra of <i>de novo</i> structural mutation in <i>Chlamydomonas reinhardtii</i>

2022-05-23

Abstract excerpt

Genetic variation originates from several types of spontaneous mutation, including single nucleotide substitutions, short insertions and deletions (INDELs), and larger structural changes. Structural mutations (SMs) drive genome evolution and are thought to play major roles in evolutionary adaptation, speciation and genetic disease, including cancers. Sequencing of mutation accumulation (MA) lines has provided esti...

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Literature Corpus work: c86a898c-12b2-53e8-a648-ccb98cc36df1
DOI: 10.1101/2022.05.23.493040

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