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Article

Nucleotide diversity in the mitochondrial and nuclear compartments of Chlamydomonas reinhardtii: investigating the origins of genome architecture.

BMC evolutionary biology - 21 May 2008

Smith David Roy, Lee Robert W

Abstract excerpt

BACKGROUND: The magnitude of intronic and intergenic DNA can vary substantially both within and among evolutionary lineages; however, the forces responsible for this disparity in genome compactness are conjectural. One explanation, termed the mutational-burden hypothesis, posits that genome compactness is primarily driven by two nonadaptive processes: mutation and random genetic drift - the effects of which can...

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PMID: 18495022
DOI: 10.1186/1471-2148-8-156
PMCID: PMC2412866

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