Article

Uncovering the Dual Role of Mitochondrial and Nuclear DNA Variants in Pediatric Cardiomyopathies

2023-12-20

Abstract excerpt

<h4>ABSTRACT</h4> Myocardial defects, originating from disruptions in genes affecting mitochondrial proteins interacting with others, have received limited research attention. In our study involving 27 pediatric cardiomyopathy patients, we explored mitochondrial and nuclear genes for four main cardiomyopathy subtypes. Sequencing cardiomyopathy-associated genes in patients was followed by whole mtDNA sequencing in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c843b22f-ec0b-511d-aaef-fd2a0089c867
DOI: 10.1101/2023.12.20.23300082

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Uncovering the Dual Role of Mitochondrial and Nuclear DNA Variants in Pediatric CardiomyopathiesDOI 10.1101/2023.12.20.23300082Read

Investigating the dual role of mitochondrial and nuclear genome variants in pediatric cardiomyopathiesSemantic proximity Read

[Advances in the molecular genetics of nuclear gene mutations causing pediatric mitochondrial cardiomyopathy].Semantic proximity Read

Genetic Profile of Left Ventricular Noncompaction Cardiomyopathy in Children—A Single Reference Center ExperienceSemantic proximity Read

Mitochondrial DNA related cardiomyopathies.Semantic proximity Read

Molecular analysis of dilated and left ventricular noncompaction cardiomyopathies in Egyptian children.Semantic proximity Read

Cardiomyopathy in children: a single-centre, retrospective study of genetic and clinical characteristics.Semantic proximity Read

Investigating TNNC1 gene inheritance and clinical outcomes through a comprehensive familial study.Semantic proximity Read

Age and Sex Differences in the Genetics of CardiomyopathySemantic proximity Read

Molecular Epidemiology of Mitochondrial Cardiomyopathy: A Search Among Mitochondrial and Nuclear Genes.Semantic proximity Read

Genetic Analysis of Patients with Left Ventricular Noncompaction: Identification of Novel Candidate VariantsSemantic proximity Read

Sarcomere gene variants did not improve cardiac function in pediatric patients with dilated cardiomyopathy from Japanese cohortsSemantic proximity Read

Pediatric mitochondrial diseases and the heart.Semantic proximity Read