Article

Age and Sex Differences in the Genetics of Cardiomyopathy

2021-04-08

Abstract excerpt

<h4>Aims</h4> Cardiomyopathy is a clinically and genetically heterogeneous disorder with age and sex-related differences in severity and outcomes. The aim of our study was to identify age and sex-related differences in the genetic architecture of cardiomyopathy. <h4>Methods and Results</h4> We analyzed whole genome sequence data from 471 pediatric and 926 adult cardiomyopathy patients from our Heart Centre Biobank...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6a174587-1edf-5345-ae96-134825fda373
DOI: 10.1101/2021.04.06.21255002

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Age and Sex Differences in the Genetics of CardiomyopathyDOI 10.1101/2021.04.06.21255002Read

Age and Sex Differences in the Genetics of Cardiomyopathy.Semantic proximity Read

Sex and Age Specific Genetic Risk Across the Dilated and Arrhythmogenic Cardiomyopathy Spectrum: Insights From the SHaRe Registry.Semantic proximity Read

Population-based variation in cardiomyopathy genes.Semantic proximity Read

Genetic Basis of Childhood CardiomyopathySemantic proximity Read

Molecular analysis of dilated and left ventricular noncompaction cardiomyopathies in Egyptian children.Semantic proximity Read

The genetic architecture of pediatric cardiomyopathy.Semantic proximity Read

Clinical and Mechanistic Insights Into the Genetics of Cardiomyopathy.Semantic proximity Read

A Wide and Specific Spectrum of Genetic Variants and Genotype-Phenotype Correlations Revealed by Next-Generation Sequencing in Patients with Left Ventricular Noncompaction.Semantic proximity Read

Cardiomyopathy in children: a single-centre, retrospective study of genetic and clinical characteristics.Semantic proximity Read

Genetic heterogeneity of cardiomyopathy and its correlation with patient careSemantic proximity Read

Exploring TTN variants as genetic insights into cardiomyopathy pathogenesis and potential emerging clues to molecular mechanisms in cardiomyopathiesSemantic proximity Read

Meta-analysis of cardiomyopathy-associated variants in troponin genes identifies loci and intragenic hot spots that are associated with worse clinical outcomes.Semantic proximity Read