Metagenomics or Metataxonomics: Best Practice Methods to Uncover the Sinus Microbiome

Abstract excerpt

<title>Abstract</title> <p>Background Dysbiosis of the human microbiome has been linked to many chronic diseases including chronic rhinosinusitis (CRS). Advances in next generation sequencing have improved our ability to identify difficult-to-culture bacteria, many of which populate the sinuses. However, methods of microbiome analysis have not been benchmarked in the sinuses, and sequencing workflows have been b...

Topics

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• Cystic Fibrosis Research Advances
• Ear Surgery and Otitis Media
• Gut microbiota and health
• Head and Neck Surgical Oncology
• Oral microbiology and periodontitis research
• Salivary Gland Tumors Diagnosis and Treatment
• Sinusitis and nasal conditions
• Tracheal and airway disorders

Identifiers and source

Literature Corpus work

c795c750-a4cd-5f82-9b79-f313af008fe5

DOI

10.21203/rs.3.rs-4332600/v1