Article

Decomposing the Apoptosis Pathway Into Biologically Interpretable Principal Components

2017-12-21

Abstract excerpt

Principal component analysis (PCA) is one of the most common techniques in the analysis of biological data sets, but applying PCA raises two challenges. First, one must determine the number of significant principal components (PCs). Second, because each PC is a linear combination of genes, it rarely has a biological interpretation. Existing methods to determine the number of PCs are either subjective or computatio...

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Literature Corpus work: c6eaf0ef-7575-5557-8d44-4f68836fe58a
DOI: 10.1101/237883

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