Article
CXCL2-mediated ATR/CHK1 Signaling Pathway and Platinum Resistance in Epithelial Ovarian Cancer
2021-04-07
Abstract excerpt
<title>Abstract</title> <p>Tumor microenvironment and chemokines play a significant role in cancer chemoresistance. This study was designed to reveal the important role of CXCL2 in platinum resistance in epithelial ovarian cancer (EOC). Differently expressed (DE) genes were screen out based on analysis of GSE114206 dataset in GEO database. The expression of DE chemokines was further validated in platinum- resista...
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Identifiers and source
- Literature Corpus work
- c6aa329a-4bd6-58c6-bdc1-b78527f7ecdc
- DOI
- 10.21203/rs.3.rs-397447/v1
