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Differential base-sharing between humans and Neanderthals: inter-breeding or greater mutability in heterozygotes?

2019-06-07

Abstract excerpt

The idea that humans interbred with other Hominins, most notably Neanderthals, is now accepted as fact. The finding of hybrid skeletons shows that fertile matings did occur. However, inferences about the size of the resulting legacy assume that back-mutations are rare enough to be ignored and that mutation rate does not vary. In reality, back-mutations are common, mutation rate does vary between populations and th...

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Literature Corpus work
c62c4af3-66fb-5913-acaf-71b3bd1927ba
DOI
10.1101/664581
Open publication

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Differential base-sharing between humans and Neanderthals: inter-breeding or greater mutability in heterozygotes?DOI 10.1101/664581
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