Article

Genome scans of dog behavior implicate a gene network underlying psychopathology in mammals, including humans

2020-07-19

Abstract excerpt

Genetic studies show a general factor associated with all human psychopathology and strongly correlated with personality and intelligence, but its basis is unknown. We performed genome scans of 17 normal and problem behaviors in three multi-breed dog cohorts. 21 of 90 mapped loci were supported for the same, or a related, trait in a second cohort. Several of those loci were also associated with brain structure dif...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c52b1f6d-b540-52dc-abc0-8a3166e79e13
DOI: 10.1101/2020.07.19.211078

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genome scans of dog behavior implicate a gene network underlying psychopathology in mammals, including humansDOI 10.1101/2020.07.19.211078Read

Genetic testing of dogs predicts problem behaviors in clinical and nonclinical samplesSemantic proximity Read

Comparative neurogenetics of dog behavior complements efforts towards human neuropsychiatric genetics.Semantic proximity Read

Deciphering the genetic basis of behavioral traits in dogs: Observed-trait GWAS and latent-trait GWAS analysis reveal key genes and variants.Semantic proximity Read

Breed Differences in Dog Cognition Associated with Brain-Expressed Genes and Neurological Functions.Semantic proximity Read

Genetic mapping of canine fear and aggression.Semantic proximity Read

Insights into morphology and disease from the dog genome project.Semantic proximity Read

Genetic architecture of the dog: sexual size dimorphism and functional morphology.Semantic proximity Read

Domestic dog lineages reveal genetic drivers of behavioral diversification.Semantic proximity Read

The canine era: the rise of a biomedical model.Semantic proximity Read

Network analysis of canine brain morphometry links tumour risk to oestrogen deficiency and accelerated brain ageingSemantic proximity Read

Leader of the pack: gene mapping in dogs and other model organisms.Semantic proximity Read

Canine behavioral genetics: pointing out the phenotypes and herding up the genes.Semantic proximity Read