Article

GRNIX: A Graph Neural Network Framework for Explainable Gene Regulatory Network Inference in Autoimmune Diseases Using XAI

2024-11-25

Abstract excerpt

Autoimmune diseases result from dysregulated immune mechanisms influenced by complex gene regulatory net-works (GRNs). Deciphering these networks has significant implications for understanding disease mechanisms, predicting disease progression, and identifying novel therapeutic targets. Traditional GRN inference techniques rely on statistical correlations or deterministic models, which are limited in capturing non...

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Literature Corpus work: c422573b-d8d1-5ae4-9217-bdf0eb5df76b
DOI: 10.1101/2024.11.24.625043

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