Back to search

Article

Bioinformatic analysis and in vitro experiments reveal that N-linked glycosylation related genes STT3A, DDOST and TMEM165 participate in the promotion of hepatocellular carcinoma and Its role in immunotherapy

2023-02-09

Abstract excerpt

<h4>Background: </h4> The complex tumor microenvironment of hepatocellular carcinoma (HCC) has led to a low response to immune checkpoints inhibitors (ICIs) and a poor prognosis. PD-L1, as one of the indications for ICIs, is rich in glycosylation modifications, which result in untimely ICIs. Our study constructed a prognostic model based on N-linked glycosylation related genes for predicting the prognosis and the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
c32fea06-40fb-5a10-8794-c5a6d09cb155
DOI
10.21203/rs.3.rs-2523951/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Bioinformatic analysis and in vitro experiments reveal that N-linked glycosylation related genes STT3A, DDOST and TMEM165 participate in the promotion of hepatocellular carcinoma and Its role in immunotherapyDOI 10.21203/rs.3.rs-2523951/v1
Glycosylation-Related Genes predict prognosis in Hepatocellular carcinomaSemantic proximity
Integrated multi-omics analysis and machine learning based on O_linked_glycosylation genes refine molecular subtypes and prognosis for hepatocellular carcinomaSemantic proximity
O-glycosylation Genes are associated with the immune microenvironment and Predict Prognosis in Esophageal carcinomaSemantic proximity
Comprehensive Bioinformatics Analysis of Glycosylation-Related Genes and Potential Therapeutic Targets in Colorectal CancerSemantic proximity
Predictive potentials of glycosylation-related genes in glioma prognosis and their correlation with immune infiltrationSemantic proximity
Prognostic modeling of glycosylation in TNBC and screening of related key genes through a comprehensive analysis of multi-omics studiesSemantic proximity
A Novel Glycosylation-Related Transcriptome Panel with Immune and Clinical Value Predicts Prognosis and Drug Sensitivity in Clear Cell Renal Cell CarcinomasSemantic proximity
Key Cancer Glycosylation-related Genes Analysis: Regulatory, Therapeutic, and Prognostic InsightsSemantic proximity
Prognostic Value and Regulatory Network of Immune-Related Genes in Hepatocellular CarcinomaSemantic proximity
Molecular Subtypes of Esophageal Squamous Cell Carcinoma Driven by N- Glycosylation and Construction of a Machine Learning-Based Prognostic ModelSemantic proximity
A Differentiation-Related Gene Prognostic Index Contributes to Prognosis and Immunotherapy Evaluation in Patients with Hepatocellular CarcinomaSemantic proximity
Application of a risk score model based on glycosylation-related genes in the prognosis and treatment of patients with low-grade gliomaSemantic proximity
Select a neighboring publication to make it the new centre.