Article
Efficient overexpression and purification of SARS-CoV-2 Nucleocapsid proteins in <i>Escherichia coli</i>
2024-01-09
Abstract excerpt
<h4>ABSTRACT</h4> The fundamental biology of Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid protein (Ncap), its use in diagnostic assays and its potential application as a vaccine component have received considerable attention since the outbreak of the Covid19 pandemic in late 2019. Here we report the scalable expression and purification of soluble, immunologically active, SARS-CoV-2 Nc...
Topics
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- Bacteriophages and microbial interactions
- COVID-19 Clinical Research Studies
- Influenza Virus Research Studies
- Monoclonal and Polyclonal Antibodies Research
- RNA and protein synthesis mechanisms
- SARS-CoV-2 and COVID-19 Research
- Viral gastroenteritis research and epidemiology
- Viral Infectious Diseases and Gene Expression in Insects
Identifiers and source
- Literature Corpus work
- c2f5e915-fe03-5018-b979-1715947702bf
- DOI
- 10.1101/2024.01.08.574531
