Article

Cerebellar White Matter Abnormalities in Patients with Charcot-Marie-Tooth disease

2021-05-25

Abstract excerpt

Charcot-Marie-Tooth disease (CMT) is a genetically heterogeneous hereditary peripheral neuropathy. Brain volumetry and diffusion tensor imaging (DTI) were performed in CMT patients with PMP22 duplication, MFN2 , GJB1 , or NEFL mutations to investigate for structural changes of the cerebellum.Volume in cerebellar white matter (WM) was significantly reduced in CMT patients with NEFL mutations. Abnormal DTI findings...

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Literature Corpus work: c277de29-8fb6-5ef8-a295-dd324bb07d3b
DOI: 10.21203/rs.3.rs-410547/v1

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