Article

Scalable Deep Learning of Histology Images Reveals Genetic and Phenotypic Determinants of Adipocyte Hypertrophy

2025-02-12

Abstract excerpt

<h4>Background</h4> White adipose tissue dysfunction has emerged as a critical factor in cardiometabolic disease development, yet the cellular microstructure and genetic architecture of adipocyte morphology remain poorly explored. <h4>Methods</h4> We introduce Adipocyte U-Net 2.0, an advanced deep learning method for the semantic segmentation of adipose tissue histology, enabling analysis of over 27 million adip...

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Literature Corpus work: c2696259-bb6a-5c9d-b64b-a89ad6f4703d
DOI: 10.1101/2025.02.11.25322053

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