Article

Short-hairpin RNA-mediated suppression of cortactin may inhibit the migration and invasion abilities of endometrial cancer cells by reducing lamellipodia

2022-03-14

Abstract excerpt

<h4>Background: </h4> Endometrial cancer (EC) is one of the most common gynecological tumors. The prognosis of EC is seriously affected by the degree of tissue infiltration and distant metastasis by tumor cells. Approximately 15–20% of patients are at high risk of distant metastasis, which carries a poor prognosis. Lamellipodia are related to the invasion and migration of tumor cells, and cortactin (CTTN) can regu...

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Literature Corpus work: c2674945-8c11-5150-9ea5-35b596066b9c
DOI: 10.21203/rs.3.rs-1438332/v1

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