Article

The phenotype and function of CD²⁵⁺CD¹²⁷⁻ regulatory T cells in rheumatoid arthritis

2013-01-01

Abstract excerpt

Regulatory T cells control many aspects of the immune system by enforcing dominant negative responses on other immune cells. Defective regulatory T cell function has been linked to many autoimmune diseases, including rheumatoid arthritis. Cytotoxic T lymphocyte antigen 4 (CTLA-4) plays a critical role in the development and function of regulatory T cells. Moreover, CTLA-4 function has been shown to be defective in...

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Literature Corpus work: c240e49c-d479-5d22-929c-3b76d3749f32
DOI: 10.25560/18039

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