Article

Airway epithelial response to RSV is impaired in multiciliated and goblet cells in asthma

2023-03-17

Abstract excerpt

In patients with asthma, respiratory syncytial virus (RSV) infections can cause disease exacerbations by infecting the epithelial layer of the airways, inducing an innate and adaptive immune response. The type-I interferon antiviral response of epithelial cells upon RSV infection is found to be reduced in asthma in most -but not all-studies. Moreover, the molecular mechanisms that cause the differences in the asth...

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Literature Corpus work: c1e2e6c6-150f-5645-aaa7-e791122f2766
DOI: 10.1101/2023.03.16.532356

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