Article
Screening of Potential Biomarkers and Therapeutic Targets for T2DM-related Alzheimer's Disease Based on Bioinformatics Analysis
2021-10-11
Abstract excerpt
More and more studies have suggested that type 2 diabetes mellitus (T2DM) was susceptible to trigger Alzheimer’s disease(AD), but the common underlying mechanism were unclear. We want to perform bioinformatic analysis with public databases. The T2DM dataset GSE95849 and AD dataset GSE97760 were selected from Gene Expression Omnibus (GEO) database. Then, we identified differentially expressed genes (DEGs) and the c...
Topics
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- Alzheimer's disease research and treatments
- Autophagy in Disease and Therapy
- Bioinformatics and Genomic Networks
- Computational Drug Discovery Methods
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological Disease Mechanisms and Treatments
- Nuclear Receptors and Signaling
- Tryptophan and brain disorders
Identifiers and source
- Literature Corpus work
- c1c91171-36c9-5b1e-b8a2-35f0f3f8d673
- DOI
- 10.21203/rs.3.rs-952508/v1
