Article

Generalized Biomolecular Modeling and Design with RoseTTAFold All-Atom

2023-10-09

Abstract excerpt

Although AlphaFold2 (AF2) and RoseTTAFold (RF) have transformed structural biology by enabling high-accuracy protein structure modeling, they are unable to model covalent modifications or interactions with small molecules and other non-protein molecules that can play key roles in biological function. Here, we describe RoseTTAFold All-Atom (RFAA), a deep network capable of modeling full biological assemblies contai...

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Literature Corpus work: c15f36a5-61a4-5608-a49d-53b6aa4a301e
DOI: 10.1101/2023.10.09.561603

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