Article

LncRNA LINC01671/YY1 positive feedback loop induced EMT modulates CCL2 secretion in colorectal cancer to attract M2-like TAM infiltration

2023-09-12

Abstract excerpt

<h4>Background: </h4> Epithelial-mesenchymal transition (EMT) is involved in the interaction between cancer cells and tumor-associated macrophages (TAMs) in the tumor microenvironment (TME), which intimately affects tumorigenicity and metastasis. However, the potential mechanisms of EMT and the understanding of how EMT-programmed cancer cells affect TAMs recruitment and polarization remain further investigation. M...

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Literature Corpus work: c1322ace-38d8-5111-adbd-71e8186309a9
DOI: 10.21203/rs.3.rs-3321885/v1

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