Back to search

Article

Impact of Nrf2 Signaling Pathway in Adipogenesis and Its Role in Insulin Resistance Associated with Obesity

2025-05-21

Abstract excerpt

A chronic positive energy balance, as observed in obesity, leads to an increase in circulating free fatty acids (FFAs), which can activate inflammatory signaling in M1 macrophages. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that controls the expression of several genes involved in the cellular response to redox changes, xenobiotic detoxification, and adipogenesis. The signaling pa...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
c06ef5a6-8160-5ecf-91b3-cbd856c1065a
DOI
10.20944/preprints202505.1688.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Impact of Nrf2 Signaling Pathway in Adipogenesis and Its Role in Insulin Resistance Associated with ObesityDOI 10.20944/preprints202505.1688.v1
New Player on An Old Field; the Keap1/Nrf2 Pathway as a Target for Treatment of Type 2 Diabetes and Metabolic SyndromeSemantic proximity
Deficiency in the Nuclear Factor E2-related Factor-2 Transcription Factor Results in Impaired Adipogenesis and Protects against Diet-induced ObesitySemantic proximity
Macrophage and Adipocyte Mitochondrial Dysfunction in Obesity-Induced Metabolic DiseasesSemantic proximity
Peroxisome Proliferator-Activated Receptor-γ: Master Regulator of Adipogenesis and ObesitySemantic proximity
Mechanisms linking endoplasmic reticulum (ER) stress and microRNAs to adipose tissue dysfunction in obesitySemantic proximity
The role of macrophage and adipocyte mitochondrial dysfunction in the pathogenesis of obesitySemantic proximity
Free Fatty Acid Receptors (FFARs) In Adipose: Physiological Role and Therapeutic OutlookSemantic proximity
The roles of NFE2L1 in adipocytes: Structural and mechanistic insight from cell and mouse modelsSemantic proximity
Adipocytes properties and crosstalk with immune system in obesity-related inflammation.Semantic proximity
The role of NRF2 function and regulation in atherosclerosis: an updateSemantic proximity
The Role of Tissue Macrophage-Mediated Inflammation on NAFLD Pathogenesis and Its Clinical Implications.Semantic proximity
Novel insights into regulators and functional modulators of adipogenesisSemantic proximity
Select a neighboring publication to make it the new centre.