Article

Umbilical Mesenchymal Stem Cell-derived Exosomes Facilitate Spinal Cord Functional Recovery Through the miR-199a-3p/145-5p-mediated NGF/TrkA Signaling Pathway in Rats

2020-12-03

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Although exosomes, as byproducts of human umbilical cord mesenchymal stem cells (hUC-MSCs), have been demonstrated to be an effective therapy for traumatic spinal cord injury (SCI), their mechanism of action remains unclear. <bold>Methods</bold> We designed and performed this study to determine whether exosomes attenuate the lesion size of SCI by ameliorating neu...

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Literature Corpus work: c06db8b1-ba25-50af-a1a2-a1fe27ba22ef
DOI: 10.21203/rs.3.rs-117436/v1

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