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The Role of Prior HBV Infection and Resistance Mutations on the Efficacy of 3TC/DTG as a Maintenance Therapy

2025-10-11

Abstract excerpt

Lamivudine/dolutegravir (3TC/DTG) is effective and safe for most people with HIV infection (PWH) who are virologically suppressed, but specific individual’s characteristics, such as previous detection of archived resistance-associated mutations (RAMs) to 3TC and prior HBV infection, could represent a risk for virological failure (VF). We conducted a retrospective monocentric cohort study to assess rates and predic...

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Literature Corpus work
c01a67e4-7f43-5db0-8054-a875641c8ffc
DOI
10.20944/preprints202510.0850.v1
Open publication

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