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Brief communication: virological outcomes and dolutegravir resistance mutations in HIV-infected patients: a multicenter retrospective cohort study in Mozambique.

AIDS research and therapy - 30 Jan 2025

Doro Altan Anna Maria, Majid Noorjehan, Orlando Stefano, Uamusse Elton, Rafael Marcia, Sidumo Zita, Guidotti Giovanni, Ciccacci Fausto

Abstract excerpt

The global HIV epidemic remains a major public health challenge, with DTG playing a key role in ART regimens due to its efficacy and tolerability. This study evaluated virological outcomes and resistance mutations in patients on DTG in Mozambique through a retrospective cohort study in seven DREAM centers. Data from 29,601 patients (98.1% on DTG) revealed a virological suppression rate of 95% (27,622/29,051)....

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Identifiers

PMID: 39885593
DOI: 10.1186/s12981-025-00708-w
PMCID: PMC11784004

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